منابع مشابه
Immature dense granules in platelets from mice with platelet storage pool disease.
Mepacrine uptake into platelets and bone marrow megakaryocytes was analyzed to further characterize the dense granule defects in a group of seven mouse pigment mutants that have characteristics of platelet storage pool disease (SPD). In contrast to our previous studies using electron microscopy, this method revealed that all mutants had normal numbers of dense granules. However, total mepacrine...
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Background: The origin and function of human leukocyte antigen (HLA) class I molecules on platelets are still highly arguable. Given the differences in the results of the previous studies in this regard, the lack of research in recent years, and the clinical importance of HLA class I molecules, the absorption capacity of platelets for soluble HLA class I molecules was studied in this investigat...
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OBJECTIVES This study sought to evaluate the platelet response to aspirin and the immature platelet fraction in patients with previous stent thrombosis (ST). BACKGROUND ST is a potentially fatal complication of coronary stenting. A reduced platelet response to aspirin increases the risk of cardiovascular events. METHODS We included 117 patients previously undergoing percutaneous coronary in...
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AIMS The influence of reticulated platelets (RPs) on platelet inhibition by ticagrelor when compared with prasugrel is unknown. We aimed to determine the influence of RPs on adenosine diphosphate- (ADP-) induced platelet aggregation in patients with acute coronary syndrome who were randomly assigned to receive either ticagrelor or prasugrel for P2Y12 receptor inhibition. METHODS AND RESULTS O...
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1Program in Human Molecular Biology and Genetics and 2Department of Surgery, University of Utah, Salt Lake City; 3Department of Nanoscale Imaging of Cellular Dynamics, Courant Research Centre Nano-Spectroscopy and X-Ray Imaging, University of Göttingen, Göttingen, Germany; 4Department of Physics and Harvard School of Engineering and Applied Sciences, Harvard University, Cambridge, MA; 5Division...
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ژورنال
عنوان ژورنال: Circulation
سال: 2016
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.116.022538